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Alkaptonuria Market Is Expected To Grow During the Forecast Period (2019-2032), DelveInsight | Key Companies- Swedish Orphan Biovitrum, and Several Others

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Alkaptonuria Market Is Expected To Grow During the Forecast Period (2019-2032), DelveInsight | Key Companies- Swedish Orphan Biovitrum, and Several Others

July 06
12:26 2022
Alkaptonuria Market Is Expected To Grow During the Forecast Period (2019-2032), DelveInsight | Key Companies- Swedish Orphan Biovitrum, and Several Others

Alkaptonuria Market Report gives readers a thorough assessment of key market drivers, restraints, prospects, opportunities, restraints, current trends, and technological and industrial breakthroughs that will influence market growth. The detailed market research, industry sector growth and development, and new product introductions covered in this report on the Alkaptonuria Market are of great assistance to the important new commercial players joining the market.


This Alkaptonuria Market report research conducts a careful market evaluation and provides a professional analysis of the industry taking into account market development, present market circumstances, and forecasts for the future. The market driving factors, market overview, industry volume, and market share are also highlighted in this Alkaptonuria Market report analysis.


Regions Covered in the Report-

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan


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Alkaptonuria: An Overview

Alkaptonuria, or “black urine disease”, is a very rare inherited disorder that prevents the body fully breaking down two protein building blocks (amino acids) called tyrosine and phenylalanine. It is a rare disorder of autosomal recessive inheritance. It is caused by a mutation in a gene that results in the accumulation of homogentisic acid (HGA). Characteristically, the excess HGA means sufferers pass dark urine, which upon standing turns black. This is a feature present from birth. Over time patients develop other manifestations of AKU, due to deposition of HGA in collagenous tissues, namely ochronosis and ochronotic osteoarthropathy.


Key highlights of the Alkaptonuria Market Report

  • As per the US National Library of Medicine, alkaptonuria is rare, affecting 1 in 250,000 to 1 million people worldwide. Alkaptonuria is more common in certain areas of Slovakia and in the Dominican Republic. Alkaptonuria is an inherited condition that causes urine to turn black when exposed to air. Ochronosis, a buildup of dark pigment in connective tissues such as cartilage and skin, is also characteristic of the disorder.
  • As per the article by Gil et al. titled “Orthopedic Manifestations of Ochronosis: Pathophysiology, Presentation, Diagnosis, and Management” alkaptonuria has an estimated prevalence ranging from 1:200,000 to 1:1,000,000 live births worldwide.
  • As per NORD, alkaptonuria affects males and females in equal numbers, although symptoms tend to develop sooner and become more severe in males.


Alkaptonuria Epidemiology Insights

Affected individuals generally do not develop symptoms (asymptomatic) during infancy or childhood and often remain unaware of their condition until adulthood. The first noticeable signs and symptoms of Alkaptonuria usually do not develop until approximately 30 years of age and are due to chronic accumulation of homogentisic acid in connective tissue, especially cartilage.


Alkaptonuria Epidemiology Segmentation in the 7MM

  • Total Prevalent Cases
  • Diagnosed and Treatable Cases


Alkaptonuria Treatment Market

Alkaptonuria is a lifelong condition – there’s currently no specific treatment or cure. The treatment of alkaptonuria is aimed at the specific symptoms that are present in each individual. Individuals with alkaptonuria often receive anti-inflammatory medications to treat joint pain. In severe cases, stronger medications such as narcotics may be recommended. Pain management is tailored to each individual’s specific case and requires long-term follow up and adjustment.


Alkaptonuria Market Insights

Alkaptonuria causes pain and stiffness, regular gentle exercise can actually help by building muscle and strengthening the joints. Exercise is also good for relieving stress, losing weight and improving your posture, all of which can ease your symptoms. The AKU Society recommends avoiding exercise that puts additional strain on the joints, such as boxing, football and rugby, and trying gentle exercise such as yoga, swimming and pilates instead.


Alkaptonuria Market Forecast

In older children and adults, high-doses of vitamin C have also been used to treat alkaptonuria because it hinders the accumulation and deposition of homogentisic acid. However, long-term use of vitamin C has generally proven ineffective and definite clinical studies on its efficacy are lacking. Hip or knee replacement, shoulder joint replacement, lumbar laminectomy, valve replacement. Any synovial joint may require arhtroplasty. Renal stone disease may require urological procedures including nephrostomy. Repair of ruptured ligaments and tendons may require a surgical approach. Any surgery required in non-Alkaptonuric patients may also be needed in AKU patients.


Alkaptonuria Market Size

Increase in the patient pool, and expected entry of emerging therapy such as Nitisinone will boost the  Alkaptonuria (AKU) market in the forecasted period (2020–2030).


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Table of Content

  1. Key Insights
  2. Executive Summary
  3. Competitive Intelligence Analysis for Alkaptonuria
  4. Alkaptonuria Market Overview at a Glance
  5. Alkaptonuria Disease Background and Overview
  6. Patient Journey
  7. Alkaptonuria Epidemiology and Patient Population
  8. Treatment Algorithm, Current Treatment, and Medical Practices
  9. Alkaptonuria Unmet Needs
  10. Key Endpoints of Alkaptonuria Treatment
  11. Alkaptonuria Marketed Products
  12. Alkaptonuria Emerging Therapies
  13. Alkaptonuria Seven Major Market Analysis
  14. Attribute analysis
  15. 7MM: Alkaptonuria Market Outlook
  16. Access and Reimbursement Overview of Alkaptonuria
  17. KOL Views
  18. Alkaptonuria Market Drivers
  19. Alkaptonuria Market Barriers
  20. Appendix
  21. DelveInsight Capabilities
  22. Disclaimer
  23. About DelveInsight


Alkaptonuria Market Report Highlights

  • In the coming years, the Alkaptonuria market is set to change due to the rising awareness of the disease, and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
  • The companies and academics are working to assess challenges and seek opportunities that could influence Alkaptonuria R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition
  • Major players are involved in developing therapies for Alkaptonuria. The launch of emerging therapies will significantly impact the Alkaptonuria market
  • A better understanding of disease pathogenesis will also contribute to the development of novel therapeutics for Alkaptonuria
  • Our in-depth analysis of the pipeline assets across different stages of development (Phase III and Phase II), different emerging trends and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities


Why should you buy this report?

  • The report will help in developing business strategies by understanding trends shaping and driving the Alkaptonuria market
  • To understand the future market competition in the Alkaptonuria market and Insightful review of the key market drivers and barriers
  • Organize sales and marketing efforts by identifying the best opportunities for Alkaptonuria in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom) and Japan
  • Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
  • Organize sales and marketing efforts by identifying the best opportunities for Alkaptonuria market
  • To understand the future market competition in the Alkaptonuria market


About Us

DelveInsight is a Business Consulting and Market research company, providing expert business solutions for life science vertical and offering quintessential advisory services in the areas of R&D, Strategy Formulation, Operations, Competitive Intelligence, Competitive Landscaping, and Mergers & Acquisitions.

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